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For the Mewtwo who appeared in Genesect and the Legend Awakened, see Mewtwo (MS016).

I was not born a Pokémon. I was created and my creators have used and betrayed me, so I stand alone!

–Mewtwo in the film Mewtwo Strikes Back

This Mewtwo is a psychic-type Legendary Pokémon. It is the cloned hybrid of Mew and also the main antagonist of the first movie, created by Professor Fuji. After Fuji's death, Giovanni found Mewtwo and convinced it to join Team Rocket.


Pokémon the Series: The Beginning

As shown at the beginning of Mewtwo Strikes Back, Mewtwo has been created by a group of scientists led by Dr. Fuji. Its companion in these early days was Ambertwo, a clone of Fuji's deceased daughter Amber, who sadly perished much like the girl she was cloned from, though he doesn't have any memories of these events except Amber's last words which was "life was wonderful", but he doesn't know why. After learning that the scientists regarded it a merely an experiment and not as a living creature of worth, it becomes filled with rage. It destroys the laboratory, and is approached by the arriving Giovanni with an offer to learn to control its powers. With some sort of armor on, Mewtwo is used in "The Battle of the Badge" against Gary Oak in a gym battle after aiding Giovanni in a series of other victories. Gary describes it as an "evil" Pokémon to Ash Ketchum, who doesn't get the chance to see it. Mewtwo escapes from Giovanni after finding out that they aren't partners, but that Giovanni regards it as a weapon. It levels Giovanni's mansion and destroys his armor in the process, and is seen briefly by Jessie and James in "It's Mr. Mime Time".

Mewtwo Strikes Back

Mewtwo subsequently returns to its birthplace, New Island, and rebuilds the lab he destroyed into a massive castle. It kidnaps the Nurse Joy of the nearest Pokémon Center, and takes control of her mind. After gaining her help in preparing for its plan to create an army of Cloned Pokémon, it has her send invitations to some strong Trainers. The Trainers go through a storm that Mewtwo used to test them, with the storm's true purpose being to wipe out all humans and those Pokémon not created through cloning as Mewtwo and his army were, as he considers natural Pokémon weak due to their willingness to serve or befriend humans. Once the trainers arrive, Mewtwo reveals himself, claiming to be both the world's strongest Pokémon trainer and the world's most powerful Pokémon.

After proving itself more than a match for several of the Pokémon assembled on the island, Mewtwo releases Nurse Joy from its control. It then accepts a challenge from Ash to prove the superiority of its cloned Pokémon, and unleashes cloned versions of Charizard, Blastoise, and Venusaur to challenge natural versions partnered with Ash and two of the other trainers. Upon achieving victory, Mewtwo captures all the trainers' Pokémon and clones them to create his army of clones, and informs the humans that it will spare them, but that they will be consumed by the storm like the rest of the planet. However, Ash then arrives with the freed natural Pokémon to challenge him, only for a far more startling opponent to appear: a living Mew.

Mewtwo challenges Mew to a battle, determined to prove that it is the superior Pokémon, which leads to a battle between the two and their respective groups of Pokémon. Using their psychic abilities, the pair suppress the abilities of the Pokémon under their leadership and engage in battle. Blind to the suffering of both sides, the two continue to clash until Ash rushes between them in a desperate attempt to stop the fighting. Their blasts render Ash inert in a stone-like state, from which it is revived by the tears of natural and cloned Pokémon alike. This sight enables Mewtwo to realize that it is one's choices, not the circumstances of their birth, that determines their identity. Dissipating its storm, he then departs with his clones and returns the humans and their Pokémon to their proper places, erasing their memories of encountering it.

Mewtwo Returns

In Mewtwo Returns, the clones have found a lovely place to live, on top of Johto's largest mountain, Mount Quena. They could live there in peace, but Giovanni finds them, having not had his memories of Mewtwo erased like everyone on New Island. In the end, he departs from the other cloned Pokémon so they can live peacefully as wild Pokémon. He is then seen in a unknown city at night.

Pokémon Journeys: The Series

Mewtwo reappears in Getting More Than You Battled For!, where he meets Goh for the first time and reunites with Ash, who are both searching for Mew. He encounters them when they fall into the mysterious island he is guarding and protecting some Pokémon. Through telepathy, Mewtwo questions their intentions, and Ash thanks him for rescuing them. After listening to Goh's dream of collecting all Pokémon and catching up with Mew, Mewtwo is moved by their determination and accepts their challenge for a battle. After he successfully defeats Pikachu, the boys send out Lucario and Cinderace against him, but none of their attack do a scratch on him. Mewtwo then easily razes the ground with a gigantic Shadow Ball, and after earning his victory asks the boys on will they continue to pursue their dreams. Receiving their affirmative answers, he understands the strong bonds they share with their Pokémon, but also reminds them that not everyone are as good as theirs, revealing that the Pokémon he has been protecting were abused and abandoned by their former Trainers. He tells the boys that they shouldn't be visiting this island, but he still thanks them for providing him such an enjoyable moment. He proceeds to depart with the Pokémon from the island, before telling the boys that their journeys have just begun.


Mewtwo's uniqueness largely stems from its psychic abilities. However, its personality is one of the defining points in the Pokémon series. Mewtwo's personality is initially complex involving existentialist anxiety, and contemplating the meaning of existence. Its temperament is very introverted, consisting of hate and anger towards humans and its creators.

Having been brought into existence through artificial means, Mewtwo quickly turned on its creators when he learned that they intended to experiment on him further. Feeling betrayed by the very humans that had created it, it decided to forge its own path. The recurring theme in the movies is Mewtwo harboring jealousy towards Mew because it is a copy or derivative, whereas Mew is the original.

In the first movie, the path that Mewtwo has taken makes him into a rather immoral character. It frequently exhibits cruelty, and, at several intervals, goes so far as to attempt to (or forthrightly) kill those who oppose it. It also shows no qualms about forcing Nurse Joy to serve as its puppet, and then casting her aside once she was of no further use to it. This makes Mewtwo easily one of the most malicious characters in the series and the main antagonist in Pokémon The First Movie, prior to its change of heart at the end of the first movie.

However, in Mewtwo Returns, it is much more kind, and only wants to protect the other clones that it created. It even protected some humans that were on a bus getting thrown around by strong winds. Therefore, Mewtwo is a hero in its second movie, and a victim. When Giovanni comes on the mountain, Mewtwo is willing to sacrifice itself to save the other clones, as well as Ash's Pikachu and Team Rocket's Meowth. Also, it constantly wants to avoid fighting, which is the exact opposite of the way he was in the first movie.

So, it can be said that Mewtwo, upon Ash's sacrifice in Mewtwo Strikes Back, has become a hero instead of a villain. It continues to live in Johto and, as said by itself, "in shadows".

Known moves

Mewtwo Strikes Back

Mewtwo Strikes Back: Evolution

Voice actors

  • Luis Bajo (Spanish)
  • Enrique Mederos (Iberial Spanish)
  • Guilherme Briggs (Portuguese)
  • Mario Zucca (Italian)
  • Jean Marc Delhausse (French)
  • Jussi Lampi (Finnish)
  • Oleg Kutsenko, Vladimir Antonik (Russian)