Salazzle, glowing with an aura, was used by Lusamine to battle Ash and co. when they approached her. Kiawe, his Marowak and Turtonator confronted her, letting the rest of the group continue on. Salazzle fired Venoshock, but was blocked by Turtonator's Flamethrower. Salazzle evaded Turtonator's Dragon Tail, but got hit by Kiawe's Marowak's Flare Blitz. Eventually, Salazzle was defeated by a combination of Turtontaor's Inferno Overdrive and Marowak's Bonemerang. Due to the Ultra Beast's control over Salazzle, she stood up and continued the battle. After Lusamine diffused with the Ultra Beast, Salazzle and the rest of her Pokémon snapped out of the Ultra Beast's control, thus ending the battle.
Before Lillie went on her journey with her family to find Mohn, she thought of Ash and the rest of her friends battling Lusamine's Pokémon, including Salazzle, to rescue Lillie's mother.