Jeanette sent Bellsprout to battle Bulbasaur. Ash, thinking Bellsprout is weak, ordered Bulbasaur to finish the battle. Bellsprout absorbed its attacks and sent it away, defeating it. Bellsprout then battled Pikachu and was not hurt by Thunderbolt as it did not conduct electricity. Pikachu tried to punch and kick it, but was defeated. Ash sent Muk, who was not hurt by Bellsprout's attacks; as a result, Bellsprout was defeated by a Body Slam from Muk.
Like its trainer, Bellsprout appeared in the opening scene of Adventures on the Orange Islands.