I have been wondering about this for a long time and I’ve thought of a lot of candidates so here are them with the reason why:
Rowlet- its the first Pokémon in the first Pokédex (Hisui)
Bulbasaur- first Pokémon in the national Pokédex
Rhydon- first designed Pokémon
Arceus- created all other Pokémon
Gengar/Nidorino- ffirst Pokémon shown in the anime (but on TV)
Dodrio- first Pokémon shown physically in the anime (as a crow in the anime)
Mew- evolved into all Pokémon
Lapras/Clefairy- were created alongside Rhydon
So what do you think? Start a debate in the comments (but keep the language appropriate please)